• vote
    3
    0 starsYemisrachBA | Shared With: Everyone - Aug 20 2007 | science, new development, genetics, RxDx
    The Pharmacogenomics Journal - Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication

    I am a bit concerned with the sample pool of "healthy subjects" for this study, which should have included more people with UM phenotype...and they are not hard to find, such decedents of Saudi Arabian and North East and horn of Africa! Overall it is an interesting results!

    This difference is only moderate but the risk for opioid intoxication might be increased in UMs if other additional factors such as reduction in renal function or further inhibition of other enzyme systems occur and the opioid intoxication risk owing to genotype might be substantial if physicians are dealing with carriers of CYP2D6 gene multiplications, which are however so rare that we did not identify any carrier or such a genotype in a screening of about 1000 healthy subjects.

    Quoted: The Pharmacogenomics Journal is dedicated to the rapid publication of original research on basic pharmacogenomics research and its clinical applications.

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    0 starsYemisrachBA | Shared With: Everyone - Dec 12 2007 | news, weather, snow, science
    Unusually Large Snowflakes Witnessed Around the World

    redot wtnr

    quoted: On January 28, 1887, in a snowstorm in Miles City, Montana, USA, a rancher witnessed the world's largest reported snowflake to date. He measured the size of the unusually large snowflake at an astonishing 15 inches (38cm) wide and 8 inches thick! Incidentally, the record holder for the highest snowfall totals are also located in the Pacific Northwest of the United States.

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    0 starsYemisrachBA | Shared With: Everyone - Oct 19 2007 | science, news
    BBC NEWS | UK | England | London | Museum drops race row scientist

    here is your trophy for idiocy

    Quoted: The Science Museum cancels a talk by American DNA pioneer Dr James Watson who claims black people are less intelligent than white people.

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    0 starsYemisrachBA | Shared With: Everyone - Oct 19 2007 | science, people, new
    James D. Watson Issues Apology for Comments About Blacks - New York Times

    I am so infuriated right now...WTH...I wonder if he will be checking into a reahab soon for what he actually has said...punk!!!!

    In an interview published Sunday in The Times of London, Dr. Watson is quoted as saying that while “there are many people of color who are very talented,” he is “inherently gloomy about the prospect of Africa.”

    “All our social policies are based on the fact that their intelligence is the same as ours — whereas all the testing says not really,” the newspaper quoted him as saying.

    In a statement given to The Associated Press yesterday, Dr. Watson said, “I cannot understand how I could have said what I am quoted as having said. There is no scientific basis for such a belief.”

    Quoted: James D. Watson, who won the Nobel prize for helping decipher DNA, apologized “unreservedly” Thursday for comments reported this week suggesting that black people, over all, are not as intelligent as whites.

  • vote
    1
    0 starsYemisrachBA | Shared With: Everyone - Oct 08 2007 | people, news, technology, science, gene manupilation
    3 Win Nobel in Medicine for Gene Manipulation - New York Times

    Quoted: Two Americans and a Briton developed a powerful technology that allows the creation of animal models of human disease in mice.

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    0 starsYemisrachBA | Shared With: Everyone - Sep 05 2007 | people, science, embryonic research, ethics
    BBC NEWS | Health | 'Human-animal' embryo green light

    Quoted: Regulators have agreed in principle to allow human-animal embryos to be created and used for research.

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    3
    0 starsYemisrachBA | Shared With: Everyone - Aug 23 2007 | ethiopia, people, science
    NPR : World's Oldest Hominid Now World's Oldest Tourist

    I am enraged with the government’s decision to prostitute one of our greatest historical pieces. Why the US? Wouldn’t it better for the country’s revenue to attract tourists to come out to Ethiopia to see Lucy? What happens to the revenue made from this and why is it confidential?

    quoted: One of the world's treasures, the fossilized hominid known as Lucy, goes on public display in Texas on Aug. 31. But controversies are swirling around the exhibition at the Houston Museum of Natural Science — the only confirmed stop so far on what the Ethiopian government hopes will be a lucrative tour.

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    5 starsYemisrachBA | Shared With: Everyone - Aug 22 2007 | people, science, web
    In Ethiopia, one man's model for a just society | csmonitor.com

    salute, my hat goes off Mr. Nuru!!!

    Quoted: He can't read or write, but Zumra Nuru created a society that would have made Karl Marx proud. The 60-year-old Ethiopian farmer founded and cochairs Awra Amba, a commune where men cook, women plow, and religion has no place.

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    1
    5 starsYemisrachBA | Shared With: Everyone - Aug 20 2007 | Science, human genetics, pharmcogenetics, Rx-Dx
    Clock genes running amok. Clock genes and their role in drug addiction and depression

    This is a remarkable finding in how microarrays can be used as part of drug/alcohol addiction treatment plan and further understand relapse

    In effect, these observations represent two sides of the same coin: drugs of abuse can influence the circadian programme, which in turn influences the effects of drugs of abuse. This dual phenomenon is caused by the action of genes that create and govern the function of the internal clock. How do these clock genes influence behaviour and physiology in response to a drug of abuse and, vice versa, how does a drug of abuse influence the action of clock genes? As drugs of abuse can transiently or permanently alter certain circadian functions, which consequently might result in a pathological condition, understanding the activity of clock genes could lead to a new understanding of—and possibly novel therapeutic approaches to treat—addiction.

    Quoted: ...there seems to be ample evidence from laboratory animals and humans that chronic drug consumption or stress might lead to circadian alterations that affect sleep ...

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    1
    0 starsYemisrachBA | Shared With: Everyone - Aug 20 2007 | news, science, new discovery, mamals
    news @ nature.com - Mice can smell greenhouse gas - Rising CO2 makes a stink for mice.

    Quoted: The exact cellular mechanism for the detection is something Luo's team is now working on. What Luo expects to be important, he says, is the ...